Santa Barbara, CA, USA – [Date] – A recently published peer-reviewed, tutorial article provides a comprehensive overview of technology and applications enabled by Optical Photothermal Infrared (O-PTIR) microscopy, a breakthrough technique that enables sub-micron infrared spectroscopy and chemical imaging.
The review article, “A Tutorial on Optical Photothermal Infrared (O-PTIR) Microscopy,” details the technology’s origins, fundamental principles, and its significant advantages over conventional infrared techniques, reviews key application areas, drawing from the growing body of publications and is authored by Professor Ji-Xin Cheng of Boston University, Dr Craig Prater, and Dr Mustafa Kansiz of Photothermal Spectroscopy Corp.
O-PTIR is an innovative infrared super-resolution technique that uses a visible probe to achieve infrared spatial resolutions up to 30 times better than traditional methods like FTIR.
This peer-reviewed tutorial outlines how O-PTIR overcomes the limitations of conventional IR microscopy, such as coarse spatial resolution and sample preparation complexities, by offering a non-contact measurement approach with visible-light-level resolution.
The article also highlights the multimodal capabilities of O-PTIR, enabling simultaneous IR and Raman spectroscopy, and co-located fluorescence microscopy, thus providing complementary chemical imaging from the same sample area.
The new high resolution, multi-modal imaging and spectroscopy technique opens up new research possibilities in fields such as biomedical sciences, environmental research, biopharmaceuticals, and materials science. The tutorial also provides a comprehensive literature review of publications across these application areas and more.
With practical insights into sample preparation, measurement configurations, and data analysis, this tutorial serves as a vital resource for scientists and researchers looking to leverage O-PTIR technology in their work.
The tutorial is available in the link below: https://pubs.aip.org/aip/app/article/9/9/091101/3312368/A-tutorial-on-optical-photothermal-infrared-O-PTIR
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